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pRTECs are interconnected by gap junctions and tight junctions, and when ferroptosis occurs in one cell, NADPH can simply diffuse from adjacent cells to the dead cell via cell junctions, thus making the adjacent cells less antioxidant and more sensitive to ferroptosis [101, 102]

10.1074/jbc.RA120.014368 57 GrenkoC

This may have seemed like a boon to pharma companies at the time, but GLP-1s are most effective as part of a more comprehensive treatment plan, tailored to the patient's individual clinical needs

As long as a drug is in shortage, it can be made off-label via compound pharmacies

It also has strong detoxification properties